STING-induced noncanonical autophagy regulates endolysosomal homeostasis

Proceedings of the National Academy of Sciences, Volume 122, Issue 8, February 2025.
SignificanceThe cGAS–STING pathway plays a key role in innate immunity by producing proinflammatory cytokines in response to cytosolic DNA. Moreover, activation of the pathway also leads to noncanonical autophagy, an evolutionarily conserved process with …